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Cognitive, Behavioral, and Sleep Characterization of Sex Differences in the Ts65Dn Mouse Model of Down syndrome

2026-08-10

Abstract excerpt

<title>Abstract</title> <p> <underline> <bold>Background</bold> </underline> : Down syndrome (DS), arising from full or partial trisomy of human chromosome 21, is the most common neurodevelopmental disability with a known genetic cause. People with DS experience altered learning, memory, and sleep. These phenotypic characteristics are exhibited in the Ts65Dn mouse, a genetically engineered murine model of DS....

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Literature Corpus work
0c6cd565-555c-56b5-a196-075a08a78076
DOI
10.21203/rs.3.rs-10516758/v1
Open publication

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Cognitive, Behavioral, and Sleep Characterization of Sex Differences in the Ts65Dn Mouse Model of Down syndromeDOI 10.21203/rs.3.rs-10516758/v1
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