Article

Validation of the BOADICEA Model in a Prospective Cohort of<i>BRCA1/2</i>Pathogenic Variant Carriers

2024-04-22

Abstract excerpt

<h4>Background</h4> No validation has been conducted for the BOADICEA multifactorial breast cancer risk prediction model specifically in BRCA1/2 pathogenic variant (PV) carriers to date. Here, we evaluated the performance of BOADICEA in predicting five-year breast cancer risks in a prospective cohort of BRCA1/2 PV carriers ascertained through clinical genetic centres. <h4>Methods</h4> We evaluated the model calibr...

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Literature Corpus work: fa783703-533e-564a-9081-684e9ce54219
DOI: 10.1101/2024.04.21.24306136

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