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Article

Type I Interferon (IFN)-Regulated Activation of Canonical and Non-Canonical Signaling Pathways

23 Nov 2020

Abstract excerpt

For several decades there has been accumulating evidence implicating type I interferons (IFNs) as key elements of the immune response. Therapeutic approaches incorporating different recombinant type I IFN proteins have been successfully employed to treat a diverse group of diseases with significant and positive outcomes. The biological activities of type I IFNs are consequences of signaling events occurring in...

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Identifiers

PMID: 33329603
DOI: 10.3389/fimmu.2020.606456

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