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Article

STAT2 and IRF9

16 Oct 2013

Abstract excerpt

Cytokine signaling is mediated by the combinatorial usage of seven STAT proteins that form homo- or heterodimers involved in the regulation of specific transcriptional programs. Among STATs, STAT2 is classically known to dimerize with STAT1 and together with IRF9 forms the ISGF3 transcription factor complex that has long been considered a hallmark of activation by type I and type III interferons. However,...

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PMID: 24498542
DOI: 10.4161/jkst.27521

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