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Article

The inflammatory response to sciatic nerve injury in a familial amyloidotic polyneuropathy mouse model.

Experimental neurology - 1 Jul 2014

Gonçalves Nádia Pereira, Teixeira-Coelho Maria, Saraiva Maria João

Abstract excerpt

Inflammation is a hallmark of several neurodegenerative disorders including familial amyloidotic polyneuropathy (FAP). FAP is associated with extracellular deposition of mutant transthyretin (TTR), leading to degeneration of cells and tissues, particularly in the peripheral nervous system (PNS). With this work, our goal was to characterize the expression/deposition of TTR and the associated inflammatory immune...

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Source

Identifiers

PMID: 24800914
DOI: 10.1016/j.expneurol.2014.04.030

Genes

TTR
FAP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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