Article

Absence of receptor for advanced glycation end product (RAGE) reduces inflammation and extends survival in the hSOD1 <sup>G93A</sup> mouse model of amyotrophic lateral sclerosis

2020-05-01

Abstract excerpt

<h4>ABSTRACT</h4> Amyotrophic lateral sclerosis (ALS) is a fatal and rapidly progressing motor neuron degenerative disease that is without effective treatment. The receptor for advanced glycation end products (RAGE) is a major component of the innate immune system that has been implicated in ALS pathogenesis. However, the contribution of RAGE signaling to the neuroinflammation that underlies ALS neurodegeneration...

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Literature Corpus work: 7abfbe8b-b00a-50e8-b4cc-49b78caddd2b
DOI: 10.1101/2020.05.01.071944

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Absence of receptor for advanced glycation end product (RAGE) reduces inflammation and extends survival in the hSOD1 <sup>G93A</sup> mouse model of amyotrophic lateral sclerosisDOI 10.1101/2020.05.01.071944Read

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