Article
Diversity of the var gene family of Indonesian Plasmodium falciparum isolates.
Malaria journal - 27 Feb 2013
Sulistyaningsih Erma, Fitri Loeki E, Löscher Thomas, Berens-Riha Nicole
Abstract excerpt
BACKGROUND: The large polymorphic protein PfEMP1 is encoded by the var gene family. PfEMP1 has been shown to play an important role as cytoadherence ligand on the surface of infected erythrocytes and thereby contributes to the distinct pathogenesis of malaria. The study explored the diversity of the DBL1α and DBL2β-C2 domains of the protein from Indonesian Plasmodium falciparum field isolates. METHODS: Samples of...
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