Differential Frequencies of HLA-DRB1, DQA1, and DQB1 Alleles and Haplotypes Are Observed in the Arbovirus-Related Neurological Syndromes.

doi:10.1093/infdis/jiaa764

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Article

Differential Frequencies of HLA-DRB1, DQA1, and DQB1 Alleles and Haplotypes Are Observed in the Arbovirus-Related Neurological Syndromes.

The Journal of infectious diseases - 2 Aug 2021

Sonon Paulin, Brito Ferreira Maria Lúcia, Santos Almeida Renata, Saloum Deghaide Neifi Hassan, Henrique Willcox Glauco, Guimarães Elizabeth Lima, da Purificação Júnior Antônio Fernando, Cordeiro Marli Tenório, Antunes de Brito Carlos Alexandre, de Albuquerque Maria de Fátima Militão, Lins Roberto D, Donadi Eduardo A, Lucena-Silva Norma

Abstract excerpt

BACKGROUND: We took advantage of the 2015-2016 Brazilian arbovirus outbreak (Zika [ZIKV]/dengue/chikungunya viruses) associated with neurological complications to type HLA-DRB1/DQA1/DQB1 variants in patients exhibiting neurological complications and in bone marrow donors from the same endemic geographical region. METHODS: DRB1/DQA1/DQB1 loci were typed using sequence-specific oligonucleotides. In silico studies...

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PMID: 33320259
DOI: 10.1093/infdis/jiaa764

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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