Article
Association of MICA and MICB alleles with symptomatic dengue infection.
Human immunology - 1 Oct 2011
García Gissel, del Puerto Florencia, Pérez Ana B, Sierra Beatriz, Aguirre Eglys, Kikuchi Mihoko, Sánchez Lizet, Hirayama Kenji, Guzmán María G
Abstract excerpt
Dengue viruses (DV) are one of the most important arthropod-borne viral diseases in the developing world. DV can cause syndromes that are either self-limiting or severe. Allelic variants of human leukocyte antigen (HLA) genes have been demonstrated to be associated with disease susceptibility. Here we report the association of nonclassical HLA class I MICA-MICB genes with disease outcome during DV infection. A...
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