Article
Clinical Sindbis alphavirus infection is associated with HLA-DRB1*01 allele and production of autoantibodies.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Aug 2012
Sane Jussi, Kurkela Satu, Lokki Marja-Liisa, Miettinen Aaro, Helve Tapani, Vaheri Antti, Vapalahti Olli
Abstract excerpt
BACKGROUND: Sindbis virus (SINV) is a mosquito-borne alphavirus found in Eurasia, Africa, and Oceania. Clinical SINV infection, characterized by arthropathic disease that may persist for years, is primarily reported in Northern Europe where the disease has considerable public health importance in endemic areas. The aim of this study was to investigate the role of genetic factors in the susceptibility and outcome...
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