Article
hUTP24 is essential for processing of the human rRNA precursor at site A1, but not at site A0.
RNA biology - 1 Jan 2015
Tomecki Rafal, Labno Anna, Drazkowska Karolina, Cysewski Dominik, Dziembowski Andrzej
Abstract excerpt
Production of ribosomes relies on more than 200 accessory factors to ensure the proper sequence of steps and faultless assembly of ribonucleoprotein machinery. Among trans-acting factors are numerous enzymes, including ribonucleases responsible for processing the large rRNA precursor synthesized by RNA polymerase I that encompasses sequences corresponding to mature 18S, 5.8S, and 25/28S rRNA. In humans, the...
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