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Article

SCFCdc4 ubiquitin ligase regulates synaptonemal complex formation during meiosis.

Life science alliance - 1 Feb 2021

Zhu Zhihui, Bani Ismail Mohammad, Shinohara Miki, Shinohara Akira

Abstract excerpt

Homologous chromosomes pair with each other during meiosis, culminating in the formation of the synaptonemal complex (SC), which is coupled with meiotic recombination. In this study, we showed that a meiosis-specific depletion mutant of a cullin (Cdc53) in the SCF (Skp-Cullin-F-box) ubiquitin ligase, which plays a critical role in cell cycle regulation during mitosis, is deficient in SC formation. However, the...

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Identifiers

PMID: 33293336
DOI: 10.26508/lsa.202000933
PMCID: PMC7756916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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