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Article

Cytology-based Detection of Circulating Tumour Cells in Human Pancreatic Cancer Xenograft Models With KRAS Mutation.

Anticancer research - 1 Dec 2020

Ito Yukako, Inoue Eriko, Matsui Yuki, Kobuchi Shinji, Moyama Chiami, Amagase Kikuko, Yoshimura Mayumi, Ikehara Yuzuru, Nakata Susumu, Nakanishi Hayao

Abstract excerpt

BACKGROUND/AIM: To examine the dynamics of circulating tumour cells (CTCs) in pancreatic cancer (PC), new mouse CTC models from human PC xenografts were developed. MATERIALS AND METHODS: Orthotopic (pancreas) and heterotopic (subcutaneous) transplantation models using GFP-tagged SUIT-2 PC cells were prepared. Using a cytology-based CTC detection platform, CTCs and metastasis were compared. RESULTS: The two types...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33288571
DOI: 10.21873/anticanres.14701

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