Article
Generation and characterisation of novel pancreatic adenocarcinoma xenograft models and corresponding primary cell lines.
PloS one - 1 Jan 2014
Wennerström Anna B, Lothe Inger Marie Bowitz, Sandhu Vandana, Kure Elin H, Myklebost Ola, Munthe Else
Abstract excerpt
Pancreatic adenocarcinoma is one of the most lethal cancer types, currently lacking efficient treatment. The heterogeneous nature of these tumours are poorly represented by the classical pancreatic cell lines, which have been through strong clonal selection in vitro, and are often derived from metastases. Here, we describe the establishment of novel pancreatic adenocarcinoma models, xenografts and corresponding...
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