Article
KRAS mutations in pancreatic circulating tumor cells: a pilot study.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2016
Kulemann Birte, Liss Andrew S, Warshaw Andrew L, Seifert Sindy, Bronsert Peter, Glatz Torben, Pitman Martha B, Hoeppner Jens
Abstract excerpt
Pancreatic ductal adenocarcinoma (PDAC) is most often diagnosed in a metastatic stage. Circulating tumor cells (CTC) in the blood are hypothesized as the means of systemic dissemination. We aimed to isolate and characterize CTC to evaluate their significance as prognostic markers in PDAC. Blood obtained from healthy donors and patients with PDAC before therapy was filtered with ScreenCell® filtration devices for...
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