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Article

Molecular clock of HIV-1 envelope genes under early immune selection.

Retrovirology - 1 Jun 2016

Park Sung Yong, Love Tanzy M T, Perelson Alan S, Mack Wendy J, Lee Ha Youn

Abstract excerpt

BACKGROUND: The molecular clock hypothesis that genes or proteins evolve at a constant rate is a key tool to reveal phylogenetic relationships among species. Using the molecular clock, we can trace an infection back to transmission using HIV-1 sequences from a single time point. Whether or not a strict molecular clock applies to HIV-1's early evolution in the presence of immune selection has not yet been fully...

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Share to env Gene Products, Human Immunodeficiency Virus
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, env

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Share to Models, Genetic

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Source

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Identifiers

PMID: 27246201
DOI: 10.1186/s12977-016-0269-6
PMCID: PMC4888660

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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