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Article

Inadequate Immune Humoral Response against JC Virus in Progressive Multifocal Leukoencephalopathy Non-Survivors.

Viruses - 2 Dec 2020

Solis Morgane, Guffroy Aurélien, Lersy François, Soulier Eric, Gallais Floriane, Renaud Mathilde, Douiri Nawal, Argemi Xavier, Hansmann Yves, De Sèze Jérôme, Kremer Stéphane, Fafi-Kremer Samira

Abstract excerpt

JC virus (JCV) causes progressive multifocal leukoencephalopathy (PML) in immunosuppressed patients. There is currently no effective specific antiviral treatment and PML management relies on immune restoration. Prognosis markers are crucially needed in this disease because of its high mortality rate. In this work, we investigated the compartmentalization of JCV strains as well as the humoral neutralizing response...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33276614
DOI: 10.3390/v12121380
PMCID: PMC7761562

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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