Article
[New trends in progressive multifocal leukoencephalopathy].
Revue neurologique - 1 Jan 2006
Gasnault J, Taoufik Y
Abstract excerpt
Infection by Polyomavirus JC is a model of chronic active viral infection, closely controlled by the immune system. Progressive multifocal leucoencephalopathy (PML) is a deadly demyelinating disease of the central nervous system, consecutive to the lytic infection of oligodendrocytes by JC virus. Reactivation of JC virus occurs only in the setting of severe cellular immune deficiency. During the last 25 years,...
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