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Pathogenesis of Progressive Multifocal Leukoencephalopathy—Revisited

12 Jan 2011

Abstract excerpt

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system that is rare even though the proven etiological agent of PML, the polyomavirus JC (JC virus), is ubiquitous within the human population. The common feature of PML cases appears to be underlying immunosuppression, and PML has gained clinical visibility because of its association with human immunodeficiency...

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PMID: 21227915
DOI: 10.1093/infdis/jiq097

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