Article
The human JC polyomavirus (JCPyV): virological background and clinical implications.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Aug 2013
Hirsch Hans H, Kardas Piotr, Kranz Denise, Leboeuf Celine
Abstract excerpt
JC polyomavirus (JCPyV) was the first of now 12 PyVs detected in humans, when in 1964, PyV particles were revealed by electron microscopy in progressive multifocal leukoencephalopathy (PML) tissues. JCPyV infection is common in 35-70% of the general population, and the virus thereafter persists in the renourinary tract. One third of healthy adults asymptomatically shed JCPyV at approximately 50,000 copies/mL...
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