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Characterization of TMAO productivity from carnitine challenge facilitates personalized nutrition and microbiome signatures discovery

19 Nov 2020

Abstract excerpt

The capability of gut microbiota in degrading foods and drugs administered orally can result in diversified efficacies and toxicity interpersonally and cause significant impact on human health. Production of atherogenic trimethylamine N-oxide (TMAO) from carnitine is a gut microbiota-directed pathway and varies widely among individuals. Here, we demonstrated a personalized TMAO formation and carnitine...

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PMID: 33213511
DOI: 10.1186/s40168-020-00912-y

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