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Methodological considerations for the identification of choline and carnitine-degrading bacteria in the gut

19 Apr 2018

Abstract excerpt

The bacterial formation of trimethylamine (TMA) has been linked to cardiovascular disease. This review focuses on the methods employed to investigate the identity of the bacteria responsible for the formation of TMA from dietary choline and carnitine in the human gut. Recent studies have revealed the metabolic pathways responsible for bacterial TMA production, primarily the anaerobic glycyl radical-containing,...

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PMID: 29684641
DOI: 10.1016/j.ymeth.2018.03.012

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