Article
BAP1-Mutated Clear Cell Renal Cell Carcinoma.
American journal of clinical pathology - 26 Apr 2021
Gallan Alexander J, Parilla Megan, Segal Jeremy, Ritterhouse Lauren, Antic Tatjana
Abstract excerpt
OBJECTIVES: While aberrations in the VHL gene and chromosome 3p resulting in clear cell renal cell carcinoma (CCRCC) are well established, we know that additional mutations in chromatin remodeling genes PBRM1, SETD2, and BRCA1-associated protein 1 (BAP1) contribute to pathogenesis in some cases. Given the known aggressive clinical behavior of BAP1-mutated CCRCC, we sought to define the pathologic phenotype of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
