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Article

BAP1 immunohistochemistry predicts outcomes in a multi-institutional cohort with clear cell renal cell carcinoma.

The Journal of urology - 1 Mar 2014

Kapur Payal, Christie Alana, Raman Jay D, Then Matthew T, Nuhn Philipp, Buchner Alexander, Bastian Patrick, Seitz Christian, Shariat Shahrokh F, Bensalah Karim, Rioux-Leclercq Nathalie, Xie Xian-Jin, Lotan Yair, Margulis Vitaly, Brugarolas James

Abstract excerpt

PURPOSE: Mutations in the tumor suppressor gene BAP1 occur in approximately 15% of clear cell renal cell carcinoma cases. Sequencing efforts demonstrated worse outcomes in patients with BAP1 mutated clear cell renal cell carcinoma. We investigated the clinicopathological significance and oncologic outcomes of BAP1 loss using a previously validated immunohistochemical assay. MATERIALS AND METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24076305
DOI: 10.1016/j.juro.2013.09.041

Genes

BAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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