Article
Evaluation of the prognostic potential of EGFL7 in pilocytic astrocytomas.
Neuropathology : official journal of the Japanese Society of Neuropathology - 1 Feb 2021
Brunhara Bruno B, Becker Aline P, Neder Luciano, Gonçalves Paola G, de Oliveira Cristiane, Clara Carlos A, Reis Rui M, Bidinotto Lucas T
Abstract excerpt
Pilocytic astrocytoma (PA) is the most frequent solid neoplasm in childhood. It has a good 5-year overall survival (90% in childhood and 52% in adults). However, up to 20% of patients experience residual tumor growth, recurrence, and death. Although the main genetic alteration of PAs, including KIAA1549:BRAF fusion, involves chromosome 7q34, we previously found frequent loss in chr9q34.3 locus in a small subset...
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