Article
High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas.
Oncogene - 7 Aug 2008
Deshmukh H, Yeh T H, Yu J, Sharma M K, Perry A, Leonard J R, Watson M A, Gutmann D H, Nagarajan R
Abstract excerpt
Pilocytic astrocytomas (PAs, WHO grade I) are the most common brain tumors in the pediatric and adolescent population, accounting for approximately one-fifth of central nervous system tumors. Because few consistent molecular alterations have been identified in PAs compared to higher grade gliomas, we performed array comparative genomic hybridization using two independent commercial array platforms. Although whole...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.