Article
Genetics of recurrent early-onset depression (GenRED): design and preliminary clinical characteristics of a repository sample for genetic linkage studies.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 May 2003
Levinson Douglas F, Zubenko George S, Crowe Raymond R, DePaulo Raymond J, Scheftner William S, Weissman Myrna M, Holmans Peter, Zubenko Wendy N, Boutelle Sandra, Murphy-Eberenz Kathleen, MacKinnon Dean, McInnis Melvin G, Marta Diana H, Adams Philip, Sassoon Stephanie, Knowles James A, Thomas Jo, Chellis Jennifer
Abstract excerpt
This is an initial report on a six-site collaborative project, Genetics of Recurrent Early-Onset Depression (GenRED). This is a study of a large sample of families with recurrent major depressive disorder (DSM-IV) beginning by the age 30 in probands or 40 in relatives. Evidence suggests that early onset and recurrence of depressive episodes predict substantially increased risk of depression in first-degree...
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