Article
Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3.
Open biology - 1 Dec 2019
Martynova Elena, Zhao Yilin, Xie Qing, Zheng Deyou, Cvekl Ales
Abstract excerpt
Gata3 is a DNA-binding transcription factor involved in cellular differentiation in a variety of tissues including inner ear, hair follicle, kidney, mammary gland and T-cells. In a previous study in 2009, Maeda et al. (Dev. Dyn.238, 2280-2291; doi:10.1002/dvdy.22035) found that Gata3 mutants could be rescued from midgestational lethality by the expression of a Gata3 transgene in sympathoadrenal neuroendocrine...
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