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Article

Diaphanous regulates myosin and adherens junctions to control cell contractility and protrusive behavior during morphogenesis.

Development (Cambridge, England) - 1 Mar 2008

Homem Catarina C F, Peifer Mark

Abstract excerpt

Formins are key regulators of actin nucleation and elongation. Diaphanous-related formins, the best-known subclass, are activated by Rho and play essential roles in cytokinesis. In cultured cells, Diaphanous-related formins also regulate cell adhesion, polarity and microtubules, suggesting that they may be key regulators of cell shape change and migration during development. However, their essential roles in...

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Identifiers

PMID: 18256194
DOI: 10.1242/dev.016337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Diaphanous regulates myosin and adherens junctions to control cell contractility and protrusive behavior during morphogenesis.PMID 18256194Read ↗

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