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Article

Gata3 restrains B cell proliferation and cooperates with p18INK4c to repress B cell lymphomagenesis.

Oncotarget - 27 Sept 2016

Liu Shiqin, Chan Ho Lam, Bai Feng, Ma Jinshan, Scott Alexandria, Robbins David J, Capobianco Anthony J, Zhu Ping, Pei Xin-Hai

Abstract excerpt

GATA3, a lineage specifier, controls lymphoid cell differentiation and its function in T cell commitment and development has been extensively studied. GATA3 promotes T cell specification by repressing B cell potential in pro T cells and decreased GATA3 expression is essential for early B cell commitment. Inherited genetic variation in GATA3 has been associated with lymphoma susceptibility. However, it remains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27588406
DOI: 10.18632/oncotarget.11746
PMCID: PMC5325421

Genes

GATA3
CDK4
CDK6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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