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Article

Prognostic impact of TTF-1 expression in patients with stage IV lung adenocarcinomas.

Lung cancer (Amsterdam, Netherlands) - 1 Jun 2017

Schilsky Juliana B, Ni Ai, Ahn Linda, Datta Sutirtha, Travis William D, Kris Mark G, Chaft Jamie E, Rekhtman Natasha, Hellmann Matthew D

Abstract excerpt

OBJECTIVES: Thyroid transcription factor 1 (TTF-1) is routinely tested in the diagnostic evaluation of suspected lung cancers, is commonly expressed by lung adenocarcinomas, and may modulate lung cancer biology. We examined the role of TTF-1 as a predictive and prognostic marker in patients with advanced lung adenocarcinomas. MATERIALS AND METHODS: We analyzed clinical, pathologic, and molecular features,...

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Adenocarcinoma
Adenocarcinoma of Lung
Biomarkers, Tumor
Immunohistochemistry
Neoplasm Staging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proportional Hazards Models

Thyroid Nuclear Factor 1

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Open in PubMed Open full text

Identifiers

PMID: 28625636
DOI: 10.1016/j.lungcan.2017.03.015
PMCID: PMC6423973

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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