Article
CACNA1C methylation: association with cortisol, perceived stress, rs1006737 and childhood trauma in males.
Epigenomics - 1 Oct 2020
Pennington Kyla, Klaus Kristel, Fachim Helene A, Butler Kevin, Trischel Ksenia, Dalton Caroline F, Heald Adrian, Reynolds Gavin P
Abstract excerpt
Aim: We investigated morning cortisol, stress, rs1006737 and childhood trauma relationship with CACNA1C methylation. Materials & methods: Morning cortisol release, childhood trauma and perceived stress were collected and genotyping for rs1006737 conducted in 103 adult males. Genomic DNA extracted from saliva was bisulphite converted and using pyrosequencing methylation determined at 11 CpG sites within intron 3...
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