Article

High-Dimensional Mediation Analysis for Selecting DNA Methylation Loci Mediating Childhood Trauma and Cortisol Stress Reactivity

2022-03-14

Abstract excerpt

Childhood trauma tends to influence cortisol stress reactivity through the mediating effects of DNA methylation. Houtepen et al. conducted a study to investigate the role of DNA methylation in cortisol stress reactivity and its relationship with childhood trauma. The study collected a dataset consisting of 385,882 DNA methylation loci, cortisol stress reactivity, one-dimensional score on a childhood trauma questio...

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Literature Corpus work: 8ee19bbc-8a1e-54ac-8bb1-50d1a7f757ff
DOI: 10.1080/01621459.2022.2053136

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