Interactive effects of early life stress and CACNA1C genotype on cortisol awakening response.

doi:10.1016/j.biopsycho.2018.05.002

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Article

Interactive effects of early life stress and CACNA1C genotype on cortisol awakening response.

Biological psychology - 1 Jul 2018

Klaus K, Butler K, Gutierrez H, Durrant S J, Pennington K

Abstract excerpt

The rs1006737 (A/G) single nucleotide polymorphism within the gene encoding the Cav1.2 subunit of the L-type voltage-dependent calcium channel (CACNA1C) has been strongly implicated in psychiatric disorders. In addition, calcium channels are sensitive to the effects of glucocorticoids and functional variation may contribute to altered stress responsivity. This study aimed to investigate the role of early life...

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Identifiers

PMID: 29733866
DOI: 10.1016/j.biopsycho.2018.05.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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