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Article

Cocaine addicted rats show reduced neural activity as revealed by manganese-enhanced MRI.

Scientific reports - 9 Nov 2020

Cannella Nazzareno, Cosa-Linan Alejandro, Takahashi Tatiane, Weber-Fahr Wolfgang, Spanagel Rainer

Abstract excerpt

Cocaine addiction develops as a continuum from recreational to habitual and ultimately compulsive drug use. Cocaine addicts show reduced brain activity. However, it is not clear if this condition results from individual predisposing traits or is the result of chronic cocaine intake. A translational neuroimaging approach with an animal model distinguishing non-addict-like vs. addict-like animals may help overcome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33168866
DOI: 10.1038/s41598-020-76182-3
PMCID: PMC7653042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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