Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In Vivo Evidence for Low Striatal Vesicular Monoamine Transporter 2 (VMAT2) Availability in Cocaine Abusers

30 Dec 2011

Abstract excerpt

OBJECTIVE: Positron emission tomography (PET) imaging studies in cocaine abusers have shown that low dopamine release in the striatum following an amphetamine challenge is associated with higher relapse rates. One possible mechanism that might lead to lower amphetamine-induced dopamine release is low availability of dopamine storage vesicles in the presynaptic terminals for release. Consistent with this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Forensic Toxicology and Drug Analysis
Share to Neurotransmitter Receptor Influence on Behavior
Share to Schizophrenia research and treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22193525
DOI: 10.1176/appi.ajp.2011.11010126

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In Vivo Evidence for Low Striatal Vesicular Monoamine Transporter 2 (VMAT2) Availability in Cocaine AbusersPMID 22193525Read ↗

Vesicular monoamine transporter (VMAT) regional expression and roles in pathological conditionsSemantic proximity Read ↗

D2 autoreceptors gate vulnerability to cocaine use disorderSemantic proximity Read ↗

PET imaging of dopamine D2 receptors in monkey models of cocaine abuse: genetic predisposition versus environmental modulation.Semantic proximity Read ↗

Heightened D3 dopamine receptor levels in cocaine dependence and contributions to the addiction behavioral phenotype: a positron emission tomography study with [11C]-+-PHNO.Semantic proximity Read ↗

In Vivo Assessment of Vesicular Monoamine Transporter Type 2 in Dementia With Lewy Bodies and Alzheimer DiseaseSemantic proximity Read ↗

Dopamine release in the nucleus accumbens (shell) of two lines of rats selectively bred to prefer or avoid ethanol.Semantic proximity Read ↗

Region-specific enhancement of basal extracellular and cocaine-evoked dopamine levels following constitutive deletion of the Serotonin(1B) receptor.Semantic proximity Read ↗

Acute intravenous synaptamine complex variant KB220™ "normalizes" neurological dysregulation in patients during protracted abstinence from alcohol and opiates as observed using quantitative electroencephalographic and genetic analysis for reward polymorphisms: part 1, pilot study with 2 case reports.Semantic proximity Read ↗

Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease.Semantic proximity Read ↗

Decreased Cannabinoid CB1 Receptors in Male Tobacco Smokers Examined With Positron Emission Tomography.Semantic proximity Read ↗

PE2I: A Radiopharmaceutical forIn vivoExploration of the Dopamine TransporterSemantic proximity Read ↗

Positron emission tomography imaging of the serotonin transporter in subjects with a history of alcoholism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.