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Article

Identification of quinolone derivatives as effective anti-Dengue virus agents.

Antiviral research - 1 Dec 2020

Nobori Haruaki, Uemura Kentaro, Toba Shinsuke, Sanaki Takao, Shishido Takao, Hall William W, Orba Yasuko, Sawa Hirofumi, Sato Akihiko

Abstract excerpt

Dengue virus (DENV) infection is one of the most important infectious diseases in tropical and subtropical regions around the world. Previously, we performed an initial phenotypic screening of 7000 compounds using DENV type 2 (DENV2)-infected BHK-21 cells to identify small molecules which could inhibit virus replication. In this study, we describe two novel compounds with anti-DENV2 activity, tentatively named...

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Identifiers

PMID: 33160000
DOI: 10.1016/j.antiviral.2020.104969

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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