Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Review on the Progress and Prospects of Dengue Drug Discovery Targeting NS5 RNA- Dependent RNA Polymerase

23 May 2020

Abstract excerpt

Dengue virus (DENV) infection threatens the health and wellbeing of almost 100 million people in the world. Vectored by mosquitoes, DENV may cause a severe disease in human hosts called Dengue hemorrhagic fever (DHF)/Dengue shock syndrome (DSS), which is not preventable by any known drug. In the absence of a universally-accepted vaccine, a drug capable of inhibiting DENV multiplication is an urgent and unmet...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Malaria Research and Control
Share to Mosquito-borne diseases and control
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32445444
DOI: 10.2174/1381612826666200523174753

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Review on the Progress and Prospects of Dengue Drug Discovery Targeting NS5 RNA- Dependent RNA PolymerasePMID 32445444Read ↗

Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymeraseSemantic proximity Read ↗

Identification of a Broad-Spectrum Viral Inhibitor Targeting a Novel Allosteric Site in the RNA-Dependent RNA Polymerases of Dengue Virus and NorovirusSemantic proximity Read ↗

Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infectionSemantic proximity Read ↗

Recent advances in the discovery of potent RNA-dependent RNA-polymerase (RdRp) inhibitors targeting virusesSemantic proximity Read ↗

Recent insights on anti-dengue virus (DENV) medicinal plants: review on in vitro , in vivo and in silico discoveriesSemantic proximity Read ↗

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance ProfilingSemantic proximity Read ↗

Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitorsSemantic proximity Read ↗

Antiviral Activity of an Indole-Type Compound Derived from Natural Products, Identified by Virtual Screening by Interaction on Dengue Virus NS5 ProteinSemantic proximity Read ↗

Discovering potential inhibitors against dengue virus NS5 RNA dependent RNA polymerase from local vegetables: a comparative computational studySemantic proximity Read ↗

An update on inhibitors targeting RNA-dependent RNA polymerase for COVID-19 treatment: Promises and challengesSemantic proximity Read ↗

Nucleotide and nucleoside-based drugs: past, present, and futureSemantic proximity Read ↗

Repurposing FDA-approved drugs and natural compounds to inhibit the RNA-dependent RNA polymerase domain of dengue virus 2 or dengue virus 3Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.