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Article

Identification of Compound-B, a novel anti-dengue virus agent targeting the non-structural protein 4A.

Antiviral research - 1 Jul 2018

Nobori Haruaki, Toba Shinsuke, Yoshida Ryu, Hall William W, Orba Yasuko, Sawa Hirofumi, Sato Akihiko

Abstract excerpt

Dengue virus (DENV) is the causative agent of dengue fever and dengue hemorrhagic fever/dengue shock syndrome. At present, no antiviral drugs are available for treatment DENV infections. In this study, a screening system based on a DENV-infected cell-based assay identified a novel anti-DENV agent with a benzimidazole skeleton, named Compound-B, which demonstrated antiviral activity specific to four DENV serotypes...

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Source

Identifiers

PMID: 29758236
DOI: 10.1016/j.antiviral.2018.05.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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