Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase

Abstract excerpt

Dengue is a mosquito-borne viral infection that has spread globally in recent years.Around half of the world's population, especially in the tropics and subtropics, is at risk of infection.Every year, 50-100 million clinical cases are reported, and more than 500,000 patients develop the symptoms of severe dengue infection: dengue haemorrhagic fever and dengue shock syndrome, which threaten life in Asia and Latin...

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