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Article

Coordinate Regulation of Ribosome and tRNA Biogenesis Controls Hypoxic Injury and Translation.

Current biology : CB - 11 Jan 2021

Itani Omar A, Zhong Xuefei, Tang Xiaoting, Scott Barbara A, Yan Jun Yi, Flibotte Stephane, Lim Yiting, Hsieh Andrew C, Bruce James E, Van Gilst Marc, Crowder C Michael

Abstract excerpt

The translation machinery is composed of a myriad of proteins and RNAs whose levels must be coordinated to efficiently produce proteins without wasting energy or substrate. However, protein synthesis is clearly not always perfectly tuned to its environment, as disruption of translation machinery components can lengthen lifespan and stress survival. While much has been learned from bacteria and yeast about...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33157031
DOI: 10.1016/j.cub.2020.10.001
PMCID: PMC7855744

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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