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Article

Survival from hypoxia in C. elegans by inactivation of aminoacyl-tRNA synthetases.

Science (New York, N.Y.) - 30 Jan 2009

Anderson Lori L, Mao Xianrong, Scott Barbara A, Crowder C Michael

Abstract excerpt

Hypoxia is important in a wide range of biological processes, such as animal hibernation and cell survival, and is particularly relevant in many diseases. The sensitivity of cells and organisms to hypoxic injury varies widely, but the molecular basis for this variation is incompletely understood. Using forward genetic screens in Caenorhabditis elegans, we isolated a hypoxia-resistant reduction-of-function mutant...

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Identifiers

PMID: 19179530
DOI: 10.1126/science.1166175
PMCID: PMC3739282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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