Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Eosinophils Protect Mice From Angiotensin-II Perfusion-Induced Abdominal Aortic Aneurysm.

Circulation research - 22 Jan 2021

Liu Cong-Lin, Liu Xin, Zhang Yuanyuan, Liu Jing, Yang Chongzhe, Luo Songyuan, Liu Tianxiao, Wang Yunzhe, Lindholt Jes S, Diederichsen Axel, Rasmussen Lars M, Dahl Marie, Sukhova Galina K, Lu Guanyi, Upchurch Gilbert R, Libby Peter, Guo Junli, Zhang Jinying, Shi Guo-Ping

Abstract excerpt

RATIONALE: Blood eosinophil count and ECP (eosinophil cationic protein) associate with human cardiovascular diseases. Yet, whether eosinophils play a role in cardiovascular disease remains untested. The current study detected eosinophil accumulation in human and murine abdominal aortic aneurysm (AAA) lesions, suggesting eosinophil participation in this aortic disease. OBJECTIVE: To test whether and how...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adoptive Transfer
Share to Angiotensin II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aorta, Abdominal

Share to Aortic Aneurysm, Abdominal

Share to Dilatation, Pathologic

Share to Eosinophils

Share to Mice, Knockout, ApoE

Share to Vascular Remodeling

Source

Open in PubMed Open full text

Identifiers

PMID: 33153394
DOI: 10.1161/CIRCRESAHA.120.318182
PMCID: PMC7855167

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Eosinophils Protect Mice From Angiotensin-II Perfusion-Induced Abdominal Aortic Aneurysm.PMID 33153394Read ↗

Pathophysiology of abdominal aortic aneurysms: insights from the elastase-induced model in mice with different genetic backgrounds.Semantic proximity Read ↗

Adenosine 2A receptor modulates inflammation and phenotype in experimental abdominal aortic aneurysms.Semantic proximity Read ↗

Extra- and Intraluminal Elastase Induce Morphologically Distinct Abdominal Aortic Aneurysms in Mice and Thus Represent Specific Subtypes of Human Disease.Semantic proximity Read ↗

Loss of MLKL impairs abdominal aortic aneurysm development by attenuating smooth muscle cell necroptosisSemantic proximity Read ↗

Single-Cell RNA Sequencing Deconstructs the Distribution of Immune Cells Within Abdominal Aortic Aneurysms in MiceSemantic proximity Read ↗

Reduced Nhe1 (Na+-H+ Exchanger-1) Function Protects ApoE-Deficient Mice From Ang II (Angiotensin II)-Induced Abdominal Aortic Aneurysms.Semantic proximity Read ↗

Inhibition of MLKL impairs abdominal aortic aneurysm development by attenuating smooth muscle cell necroptosisSemantic proximity Read ↗

Endothelium- and Fibroblast-Derived C-Type Natriuretic Peptide Prevents the Development and Progression of Aortic Aneurysm.Semantic proximity Read ↗

Differential gender- and species-specific formation of aneurysms using a novel method of inducing abdominal aortic aneurysms.Semantic proximity Read ↗

Pathophysiology of hypereosinophilia-associated heart diseaseSemantic proximity Read ↗

IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm developmentSemantic proximity Read ↗

Lymphangiogenesis in Abdominal Aortic Aneurysm regulates the balance between resident and circulating eosinophils via a 15-lipoxygenase-dependent mechanismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.