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Article

Involvement of Hdac3-mediated inhibition of microRNA cluster 17-92 in bronchopulmonary dysplasia development.

Molecular medicine (Cambridge, Mass.) - 3 Nov 2020

Wang Di, Hong Hui, Li Xiao-Xia, Li Jing, Zhang Zhi-Qun

Abstract excerpt

BACKGROUND: The incidence of bronchopulmonary dysplasia (BPD), a chronic lung disease of newborns, has been paradoxically rising despite medical advances. Histone deacetylase 3 (Hdac3) has been reported to be a crucial regulator in alveologenesis. Hence, this study aims to investigate the mechanism of Hdac3 in the abnormal pulmonary angiogenesis and alveolarization of BPD. METHODS: A hyperoxia-induced BPD model...

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Share to Bronchopulmonary Dysplasia
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33143661
DOI: 10.1186/s10020-020-00237-4
PMCID: PMC7640435

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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