Article

The involvement of HDAC3-mediated inhibition of microRNA cluster 17-92 in hyperoxia-mediated impairment of lung development in neonatal rats

2020-03-03

Abstract excerpt

<h4>Background</h4> The incidence of bronchopulmonary dysplasia (BPD), a chronic lung disease of newborns, has been paradoxically rising despite medical advances. Histone deacetylase 3 (HDAC3) has been reported to be a crucial regulator in alveologenesis. Hence, this study aims to investigate the mechanism of HDAC3 in the pulmonary angiogenesis and alveolarization of BPD. <h4>Methods</h4> A hyperoxia-induced mou...

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Literature Corpus work: e590fc21-aed7-5eba-b6cf-7b55421280bf
DOI: 10.1101/2020.03.01.971663

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