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Article

Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis

24 Mar 2011

Abstract excerpt

• Introduction • General concepts on class IIa HDACs - Regulation of subcellular localization - Binding partners - Catalytic activity - Class IIa HDAC orthologues in model organisms • HDAC4 - HDAC4 and differentiation - HDAC4 and cancer • HDAC5 - HDAC5 and differentiation - HDAC5 and cancer • HDAC7 - HDAC7 and vascular endothelium - Is HDAC7 a negative regulator of cell proliferation? - HDAC7 and cancer • HDAC9 -...

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PMID: 21435179
DOI: 10.1111/j.1582-4934.2011.01321.x

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