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Article

The interactive effect of genetic polymorphisms of IL-10 and COMT on cognitive function in schizophrenia.

Journal of psychiatric research - 1 Apr 2021

Wang Jiesi, Xu Hang, Wang Dongmei, Wei Gaoxia, Zhou Huixia, Wang Li, Zhou Yongjie, Zhang Xiangyang

Abstract excerpt

Dopaminergic and inflammatory systems have been proven to play an important role in the cognitive deficits of schizophrenia. Although increasing evidence indicates two systems have strong interaction, the relevant research on this interaction is still limited. Catechol-o-methyltransferase (COMT) and Interleukin-10 (IL-10) play critical functions in dopaminergic and inflammatory systems respectively, and their...

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Source

Identifiers

PMID: 33127070
DOI: 10.1016/j.jpsychires.2020.10.021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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