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Article

Association study of miR-100, miR-124-1, miR-218-2, miR-301b, miR-605, and miR-4293 polymorphisms and the risk of breast cancer in a sample of Iranian population.

Gene - 20 Mar 2018

Danesh Hiva, Hashemi Mohammad, Bizhani Fatemeh, Hashemi Seyed Mehdi, Bahari Gholamreza

Abstract excerpt

MicroRNAs (miRNAs) regulate genes expression by directly binding to the 3' untranslated region (3'UTR) of specific target mRNAs. Single nucleotide polymorphisms (SNPs) in microRNAs (miRNAs) are proposed to be important in the development of breast cancer (BC). In the present study, we conducted a case-control study with 266 BCE patients and 288 control women to examine the possible association of miRNAs...

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PMID: 29317318
DOI: 10.1016/j.gene.2018.01.025

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