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Genomic alteration profile and PD-L1 expression among different breast cancer subtypes in Chinese population and their correlations.

Cancer medicine - 1 Mar 2023

Li Kai, Cao Li, Li Cheukfai, Wu Jundong, Chen Bo, Zhang Guochun, Li Xueri, Wen Lingzhu, Jia Minghan, Wei Guangnan, Lin Jiali, Li Yingzi, Zhang Yuchen, Mok Hsiaopei, Ren Chongyang, Wang Yulei, Qi Xiaofang, Guo Lijie, Che Yue, Liao Ning

Abstract excerpt

BACKGROUD: There were limitations existing in programmed cell-death ligand 1 (PD-L1) as predictive biomarkers for breast cancer (BC), hence exploring the correlation between PD-L1 levels and other biomarkers in BC may become a very useful therapeutic clinical tool. METHODS: A total of 301 Chinese patients with different BC subtypes including 47 HR+/HER2+, 185 HR+/HER2-, 38 HR-/HER2+, and 31 triple-negative breast...

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PMID: 36404592
DOI: 10.1002/cam4.5314
PMCID: PMC10028068

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