Association of Gene Polymorphisms in Programmed Death Ligand-1 (PD-L1) with susceptibility and prognosis of B-Cell Non-Hodgkin Lymphoma in a Cohort of Egyptians

Abstract excerpt

<h4>Purpose: </h4> To investigate the possible relation between polymorphisms of PD-L1 rs4143815 and rs2890658 with the susceptibility and prognosis of B-NHL in a Cohort of Egyptians, we conducted a case-control study. <h4>Methods: </h4>: Genotyping was done using real-time polymerase chain reaction (real-time PCR) for 100 adult B-NHL patients and 100 healthy adults (controls). <h4>Results: </h4>: Our results di...

Topics

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• Apoptosis
• Case-Control Studies
• Egypt
• Lymphoma, B-Cell
• Pharmacogenomic Variants
• Polymorphism, Single Nucleotide
• Receptor Activator of Nuclear Factor-kappa B
• Risk Factors

Identifiers and source

Literature Corpus work

d6da62e2-0915-51bc-9521-a88316d034d3

DOI

10.21203/rs.3.rs-3838300/v1